There is increasing evidence regarding the link between the severity of COVID-19 and the alteration of the gut microbiota.
There is increasing evidence that severe cases of COVID-19 are associated with an imbalance in the gut microbiota.
Several factors can affect the severity of COVID-19 in patients, primarily the lack of available medical resources. However, many severe cases are observed in countries with sufficient economic resources and healthcare capabilities.
It has been determined that factors that contribute to the severity of COVID-19 cases are underlying individual conditions, such as advanced age and chronic illnesses. Furthermore, several studies indicate that age-related conditions and chronic illnesses, such as diabetes, high blood pressure, and obesity, among others, are linked to alterations in the balance of the gut microbiota.
To investigate the relationship between severe COVID-19 cases and altered gut microbiota, a review of recent studies was conducted to determine the link between gut microbiota alterations and the severity of COVID-19 infection. The research found strong evidence supporting the hypothesis that altered gut microbiota, with the consequent impairment of the protective intestinal barrier, may contribute to the development of gastrointestinal symptoms and other multi-organ complications observed in severely ill COVID-19 patients.
The intensification of this pandemic makes it urgent to implement other strategies in combination with the therapies currently used to combat this disease. Actions to restore the balance of the gut microbiota through a diversified diet rich in fiber, unprocessed foods, fermented foods, and the consumption of butyrate-producing probiotics could be a highly effective strategy against complications in COVID-19 patients.
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References
Heenam Stanley Kim. Do an Altered Gut Microbiota and an Associated Leaky Gut Affect COVID-19 Severity? mBio Jan 2021, 12 (1) e0302220; DOI: 10.1128/mBio.03022-20
David Baud, Varvara Dimopoulou Agri, Glenn R. Gibson, Gregor Reid and Eric Giannoni. The use of probiotics to flatten the curve of the COVID-19 pandemic. Front. Public Health , 08 May 2020 https://doi.org/10.3389/fpubh.2020